| The SAS System |
| Model Information | |
|---|---|
| Data Set | WORK.DAT_TWISK_L |
| Response Variable | CHG |
| Response Distribution | Gaussian |
| Link Function | Identity |
| Variance Function | Default |
| Variance Matrix Blocked By | USUBJID |
| Estimation Technique | Restricted Maximum Likelihood |
| Degrees of Freedom Method | Satterthwaite |
| Class Level Information | ||
|---|---|---|
| Class | Levels | Values |
| USUBJID | 152 | not printed |
| TRT01P | 2 | TRT CNT |
| Number of Observations Read | 304 |
|---|---|
| Number of Observations Used | 249 |
| Dimensions | |
|---|---|
| R-side Cov. Parameters | 3 |
| Columns in X | 3 |
| Columns in Z per Subject | 0 |
| Subjects (Blocks in V) | 152 |
| Max Obs per Subject | 2 |
| Optimization Information | |
|---|---|
| Optimization Technique | Dual Quasi-Newton |
| Parameters in Optimization | 3 |
| Lower Boundaries | 2 |
| Upper Boundaries | 0 |
| Fixed Effects | Profiled |
| Starting From | Data |
| Iteration History | |||||
|---|---|---|---|---|---|
| Iteration | Restarts | Evaluations | Objective Function |
Change | Max Gradient |
| 0 | 0 | 4 | 1901.4588798 | . | 0.226319 |
| 1 | 0 | 6 | 1900.1977261 | 1.26115370 | 0.071047 |
| 2 | 0 | 2 | 1900.1075543 | 0.09017181 | 0.033884 |
| 3 | 0 | 4 | 1899.8999165 | 0.20763782 | 0.022174 |
| 4 | 0 | 4 | 1899.8836774 | 0.01623909 | 0.019683 |
| 5 | 0 | 4 | 1899.8673313 | 0.01634603 | 0.008842 |
| 6 | 0 | 3 | 1899.8640199 | 0.00331146 | 0.000216 |
| 7 | 0 | 3 | 1899.8640179 | 0.00000196 | 5.233E-6 |
| Convergence criterion (GCONV=1E-8) satisfied. |
| Fit Statistics | |
|---|---|
| -2 Res Log Likelihood | 1899.86 |
| AIC (smaller is better) | 1905.86 |
| AICC (smaller is better) | 1905.96 |
| BIC (smaller is better) | 1914.94 |
| CAIC (smaller is better) | 1917.94 |
| HQIC (smaller is better) | 1909.55 |
| Generalized Chi-Square | 247.00 |
| Gener. Chi-Square / DF | 1.00 |
| Covariance Parameter Estimates | |||
|---|---|---|---|
| Cov Parm | Subject | Estimate | Standard Error |
| UN(1,1) | USUBJID | 140.22 | 17.5690 |
| UN(2,1) | USUBJID | 78.7940 | 16.0497 |
| UN(2,2) | USUBJID | 152.50 | 20.8939 |
| Solutions for Fixed Effects | ||||||
|---|---|---|---|---|---|---|
| Effect | TRT01P | Estimate | Standard Error |
DF | t Value | Pr > |t| |
| Intercept | -1.8508 | 1.3083 | 119.9 | -1.41 | 0.1598 | |
| TRT01P | TRT | -1.9588 | 1.8754 | 118.8 | -1.04 | 0.2984 |
| TRT01P | CNT | 0 | . | . | . | . |
| Type III Tests of Fixed Effects | ||||
|---|---|---|---|---|
| Effect | Num DF | Den DF | F Value | Pr > F |
| TRT01P | 1 | 118.8 | 1.09 | 0.2984 |
| TRT01P Least Squares Means | ||||||||
|---|---|---|---|---|---|---|---|---|
| TRT01P | Estimate | Standard Error |
DF | t Value | Pr > |t| | Alpha | Lower | Upper |
| TRT | -3.8096 | 1.3436 | 117.8 | -2.84 | 0.0054 | 0.05 | -6.4704 | -1.1488 |
| CNT | -1.8508 | 1.3083 | 119.9 | -1.41 | 0.1598 | 0.05 | -4.4412 | 0.7396 |
| Differences of TRT01P Least Squares Means | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| TRT01P | _TRT01P | Estimate | Standard Error | DF | t Value | Pr > |t| | Alpha | Lower | Upper |
| TRT | CNT | -1.9588 | 1.8754 | 118.8 | -1.04 | 0.2984 | 0.05 | -5.6723 | 1.7547 |