The SAS System

The GLIMMIX Procedure

Model Information
Data Set WORK.DAT_TWISK_L
Response Variable AVAL
Response Distribution Gaussian
Link Function Identity
Variance Function Default
Variance Matrix Blocked By USUBJID
Estimation Technique Restricted Maximum Likelihood
Degrees of Freedom Method Satterthwaite

Class Level Information
Class Levels Values
USUBJID 152 not printed
TRT01P 2 TRT CNT

Number of Observations Read 456
Number of Observations Used 388

Dimensions
R-side Cov. Parameters 6
Columns in X 4
Columns in Z per Subject 0
Subjects (Blocks in V) 152
Max Obs per Subject 3

Optimization Information
Optimization Technique Dual Quasi-Newton
Parameters in Optimization 6
Lower Boundaries 3
Upper Boundaries 0
Fixed Effects Profiled
Starting From Data

Iteration History
Iteration Restarts Evaluations Objective
Function
Change Max
Gradient
0 0 4 3003.1669695 . 0.087614
1 0 4 3002.9445316 0.22243781 0.019441
2 0 2 3002.9354386 0.00909303 0.016513
3 0 2 3002.9252256 0.01021301 0.006286
4 0 2 3002.9185193 0.00670628 0.003973
5 0 2 3002.9152934 0.00322588 0.006517
6 0 3 3002.9139626 0.00133079 0.003541
7 0 4 3002.910111 0.00385167 0.005584
8 0 3 3002.9076548 0.00245616 0.000946
9 0 3 3002.9075818 0.00007298 0.000499
10 0 3 3002.9075461 0.00003570 0.000139

Convergence criterion (GCONV=1E-8) satisfied.

Fit Statistics
-2 Res Log Likelihood 3002.91
AIC (smaller is better) 3014.91
AICC (smaller is better) 3015.13
BIC (smaller is better) 3033.05
CAIC (smaller is better) 3039.05
HQIC (smaller is better) 3022.28
Generalized Chi-Square 384.98
Gener. Chi-Square / DF 1.00

Covariance Parameter Estimates
Cov Parm Subject Estimate Standard
Error
UN(1,1) USUBJID 236.55 28.4856
UN(2,1) USUBJID 155.65 23.7018
UN(2,2) USUBJID 214.77 26.7641
UN(3,1) USUBJID 132.23 22.1585
UN(3,2) USUBJID 131.95 21.4027
UN(3,3) USUBJID 183.55 23.8101

Solutions for Fixed Effects
Effect TRT01P Estimate Standard
Error
DF t Value Pr > |t|
Intercept   128.34 1.2946 137.7 99.14 <.0001
ABLFLN   -1.0920 1.2064 140 -0.91 0.3669
ABLFLN*TRT01P TRT -3.6981 1.5697 118.1 -2.36 0.0201
ABLFLN*TRT01P CNT 0 . . . .

Type III Tests of Fixed Effects
Effect Num DF Den DF F Value Pr > F
ABLFLN 1 123.2 9.94 0.0020
ABLFLN*TRT01P 1 118.1 5.55 0.0201